Software for calculating IORT treatments with a LIAC HWL linac, based on precalculated Monte Carlo dose distributions in water.

Main Features:

• Visualize absorbed dose distributions of all combinations of applicators and energies
• Calculate monitor units (MU) with measured output factors at z_max
• Atmospheric pressure correction available
• Rescaling factors can be added for desired applicator/energy combinations
• Report generation in pdf
• Send data as RTPlan to Record and Verify software (only tested with MOSAIQ)
• Support for user customized data: output factors, R₉₀ values and rescaling factors.

Limitations:

• The software is intended for educational purposes
• The Monte Carlo model was fitted to the data acquired at Gregorio Marañón hospital, Madrid. Different linacs may show dosimetric differences.

Documentation:

https://kali-mc.readthedocs.io/

How to cite:

If you use Kali MC in your work, please cite the article describing the software:

Ayala R, García R, Ruiz G, Gómez S, Santos M, Álvarez A, García MJ, Soza Á, Udías JM, Ibáñez P. Kali MC: an open-source toolkit for intraoperative electron radiation therapy treatment planning. Biomed Phys Eng Express. 2026;12(3):037001. https://doi.org/10.1088/2057-1976/ae5f9d

Additional data:

Monte Carlo Phase Space Files (PSFs) that give rise to the displayed absorbed dose distributions are available here:

More information about the Monte Carlo modelling of the Liac HWL mobile accelerator can be found in:

Ayala R, Soza Á, García MJ, García R, Udías JM, Ibáñez P. Development and validation of a Monte Carlo model of a mobile accelerator for intraoperative radiation therapy. Med Phys. 2025; 52:e18040. https://doi.org/10.1002/mp.18040