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85 lines (63 loc) · 6 KB
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<svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 800 600">
<!-- Background -->
<rect width="800" height="600" fill="#f9f9f9"/>
<!-- Title -->
<text x="400" y="50" font-family="Arial, sans-serif" font-size="24" font-weight="bold" text-anchor="middle" fill="#333">Pain Circuit Safety Architecture</text>
<!-- Central Brain Region -->
<ellipse cx="400" cy="180" rx="120" ry="80" fill="#fff" stroke="#333" stroke-width="2"/>
<text x="400" y="170" font-family="Arial, sans-serif" font-size="16" font-weight="bold" text-anchor="middle" fill="#333">Rat Pain Circuits</text>
<text x="400" y="195" font-family="Arial, sans-serif" font-size="12" text-anchor="middle" fill="#333">(Safety Control System)</text>
<!-- Pain Circuit Components -->
<circle cx="340" cy="160" r="25" fill="#ffcdd2" stroke="#d32f2f" stroke-width="1.5"/>
<text x="340" cy="160" font-family="Arial, sans-serif" font-size="10" text-anchor="middle" fill="#b71c1c">PAG</text>
<circle cx="400" cy="160" r="25" fill="#ffcdd2" stroke="#d32f2f" stroke-width="1.5"/>
<text x="400" cy="160" font-family="Arial, sans-serif" font-size="10" text-anchor="middle" fill="#b71c1c">ACC</text>
<circle cx="460" cy="160" r="25" fill="#ffcdd2" stroke="#d32f2f" stroke-width="1.5"/>
<text x="460" cy="160" font-family="Arial, sans-serif" font-size="10" text-anchor="middle" fill="#b71c1c">Insula</text>
<!-- Nociceptive Receptors Box -->
<rect x="50" y="150" width="150" height="140" rx="10" ry="10" fill="#fff" stroke="#d32f2f" stroke-width="2"/>
<text x="125" y="175" font-family="Arial, sans-serif" font-size="14" font-weight="bold" text-anchor="middle" fill="#b71c1c">Nociceptive</text>
<text x="125" y="195" font-family="Arial, sans-serif" font-size="14" font-weight="bold" text-anchor="middle" fill="#b71c1c">Receptors</text>
<rect x="70" y="210" width="110" height="25" rx="5" ry="5" fill="#ffebee" stroke="#d32f2f" stroke-width="1"/>
<text x="125" y="227" font-family="Arial, sans-serif" font-size="10" text-anchor="middle" fill="#b71c1c">TRP Channels</text>
<rect x="70" y="240" width="110" height="25" rx="5" ry="5" fill="#ffebee" stroke="#d32f2f" stroke-width="1"/>
<text x="125" y="257" font-family="Arial, sans-serif" font-size="10" text-anchor="middle" fill="#b71c1c">ASICs</text>
<rect x="70" y="270" width="110" height="25" rx="5" ry="5" fill="#ffebee" stroke="#d32f2f" stroke-width="1"/>
<text x="125" y="287" font-family="Arial, sans-serif" font-size="10" text-anchor="middle" fill="#b71c1c">Purinergic Receptors</text>
<!-- Neurotransmitter Systems Box -->
<rect x="600" y="150" width="150" height="140" rx="10" ry="10" fill="#fff" stroke="#9c27b0" stroke-width="2"/>
<text x="675" y="175" font-family="Arial, sans-serif" font-size="14" font-weight="bold" text-anchor="middle" fill="#6a1b9a">Neurotransmitter</text>
<text x="675" y="195" font-family="Arial, sans-serif" font-size="14" font-weight="bold" text-anchor="middle" fill="#6a1b9a">Systems</text>
<rect x="620" y="210" width="110" height="25" rx="5" ry="5" fill="#f3e5f5" stroke="#9c27b0" stroke-width="1"/>
<text x="675" y="227" font-family="Arial, sans-serif" font-size="10" text-anchor="middle" fill="#6a1b9a">GABAergic</text>
<rect x="620" y="240" width="110" height="25" rx="5" ry="5" fill="#f3e5f5" stroke="#9c27b0" stroke-width="1"/>
<text x="675" y="257" font-family="Arial, sans-serif" font-size="10" text-anchor="middle" fill="#6a1b9a">Glutamatergic</text>
<rect x="620" y="270" width="110" height="25" rx="5" ry="5" fill="#f3e5f5" stroke="#9c27b0" stroke-width="1"/>
<text x="675" y="287" font-family="Arial, sans-serif" font-size="10" text-anchor="middle" fill="#6a1b9a">Serotonergic</text>
<!-- Safety Layer 1: Circuit Breaker -->
<rect x="100" y="350" width="600" height="60" rx="10" ry="10" fill="#e8f5e9" stroke="#4caf50" stroke-width="2.5"/>
<text x="400" y="385" font-family="Arial, sans-serif" font-size="16" font-weight="bold" text-anchor="middle" fill="#2e7d32">Safety Layer 1: Circuit Breaker System</text>
<!-- Safety Layer 2: Monitoring -->
<rect x="100" y="420" width="600" height="60" rx="10" ry="10" fill="#fff8e1" stroke="#ffc107" stroke-width="2.5"/>
<text x="400" y="455" font-family="Arial, sans-serif" font-size="16" font-weight="bold" text-anchor="middle" fill="#ff8f00">Safety Layer 2: Continuous Monitoring</text>
<!-- Safety Layer 3: Physiological -->
<rect x="100" y="490" width="600" height="60" rx="10" ry="10" fill="#e3f2fd" stroke="#2196f3" stroke-width="2.5"/>
<text x="400" y="525" font-family="Arial, sans-serif" font-size="16" font-weight="bold" text-anchor="middle" fill="#0d47a1">Safety Layer 3: Physiological Safeguards</text>
<!-- Arrows and Connections -->
<path d="M200,180 L280,180" stroke="#d32f2f" stroke-width="1.5" fill="none"/>
<polygon points="280,180 270,175 270,185" fill="#d32f2f"/>
<path d="M520,180 L600,180" stroke="#9c27b0" stroke-width="1.5" fill="none"/>
<polygon points="600,180 590,175 590,185" fill="#9c27b0"/>
<!-- Brain to Safety Layers -->
<path d="M400,260 Q400,300 400,350" stroke="#2e7d32" stroke-width="2" fill="none"/>
<polygon points="400,350 395,340 405,340" fill="#2e7d32"/>
<path d="M350,260 Q350,340 350,420" stroke="#ff8f00" stroke-width="2" fill="none"/>
<polygon points="350,420 345,410 355,410" fill="#ff8f00"/>
<path d="M450,260 Q450,370 450,490" stroke="#0d47a1" stroke-width="2" fill="none"/>
<polygon points="450,490 445,480 455,480" fill="#0d47a1"/>
<!-- Key Features Box -->
<rect x="250" y="270" width="300" height="70" rx="5" ry="5" fill="#fff" stroke="#333" stroke-width="1.5"/>
<text x="400" y="290" font-family="Arial, sans-serif" font-size="14" font-weight="bold" text-anchor="middle" fill="#333">Key Safety Features</text>
<text x="400" y="310" font-family="Arial, sans-serif" font-size="12" text-anchor="middle" fill="#333">• Thalamocortical activity monitoring</text>
<text x="400" y="330" font-family="Arial, sans-serif" font-size="12" text-anchor="middle" fill="#333">• Reticular formation activation detection</text>
</svg>