ustc_software2013_wiki/Preview.html at main · monetjoe/ustc_software2013_wiki · GitHub

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<head>
    <meta charset="UTF-8">
    <title>Future Work</title>
    <link rel="stylesheet" href="./assets/css/future.css" type="text/css" />
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    <div id="direction">
        <ul>
            <li><a href="#TT" class="button">Regulation Prediction</a></li>
            <li><a href="#TG" class="button">Simulation</a></li>
            <li><a href="#TI" class="button">Converse Prediction Accuracy</a></li>
            <li><a href="#TI" class="button">Visualization GUI</a></li>
            <li><a href="#main" class="button">Top</a></li>
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        <h1>Future Work</h1>
        <div id="TT" style="margin-top:0px;">
            <h2 align="justify">Regulation Prediction</h2>
            <p align="justify">There will be a room for improvement in calculating regulation by alignment. We use
                global alignment in our software now, but actually in biological field, local alignment is also very
                important. As a result, combining global alignment with local alignment gives a better calculation. On
                the other hand, we use BLOSM50 to score the alignment but whether this scoring mechanism is suitable for
                calculating regulation needs to be verified. And using machine learning to optimize our scoring
                mechanism will be our future goal. Suitable is the best! It will be a part our future work enhancing the
                efficiency of alignment. Better alignment method and backtrace model will make our software more
                excellent dealing with giant and complex network!</p>

            <p align="justify">Meanwhile, it is feasible to some extent that using alignment to predict the regulation,
                but concerning the other information about interaction such as operator, protein second structure would
                be more helpful. Focusing on the core of regulation is the key of analyzing!</p>
        </div>
        <div id="TG">
            <h2 align="justify">Simulation</h2>
            <p align="justify">Hill equation we used is universal in lots of field and as a result it will cause the low
                accuracy in network modeling. Finding an appropriate equation is really important. Chemical master
                equation needs a large amount of calculation, so finding a equilibrium point between accuracy and speed
                will be an important part of our future work.</p>
            <p align="justify">There will be a lot of uncertainty in biological process, simply mathematical equation is
                hard to simulate the high coupling in biology. How to decouple and enhance the accuracy of mathematical
                simulation will also be a part. In the same time, it will be a good attempt to add other ways of
                simulation.</p>
        </div>
        <div id="TI">
            <h2 align="justify">Converse Prediction Accuracy</h2>
            <p align="justify">PSO algorithm depends on the number of particles and precision, but it will increase the
                time of calculation, of course. We are trying to combine different optimal methods such as genetic
                algorithm, machine learning, annealing algorithm which could take a big part in finding best solution.
            </p>
            <p align="justify">For giving a better directivity, we are trying to pick out the really useful data of
                prediction to the users. And users could choose what they need more efficiently.</p>
        </div>
        <div id="TI">
            <h2 align="justify">Visualization GUI</h2>
            <p align="justify">A fantastically visualized UI is a key point of good software, more friendly control,
                more vivid data visualization, better network output. All of them will be a big part of our future work
                that improving the aesthetics and interactivity of GUI. </p>
        </div>
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